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According to the ancient Indian Sankhya philosophy, there are three qualities or aspects (Gunas) of energy and mind: Sattva (light), Rajas (activity) and Tamas (inertia). Placed in relation to the environment or physical world, the three Gunas describe the quality of human experience. The lecture will examine the neurophysiological correlates of the Gunas and demonstrate their differentiation using yoga postures and sensory experiences. There will also be discussion of neurotransmitters and functional networks in the brain.